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News
Shared Genetic Architecture Links IBD With Multiple Psychiatric Disorders
3+ day, 2+ hour ago (307+ words) Inflammatory bowel disease (IBD) shares a significant genetic architecture with several psychiatric disorders, supporting the existence of common neuroimmune and gut–brain axis mechanisms that may contribute to their frequent comorbidity. These study findings were published in the European Archives…...
Interpersonal Trauma May Worsen CDS Symptoms in Adolescents
1+ mon, 1+ week ago (323+ words) Self-reported interpersonal trauma exposure is positively associated with a higher severity of cognitive disengagement syndrome (CDS) symptoms among early adolescents, according to study findings published in European Child & Adolescent Psychiatry. Childhood trauma exposure is linked to several negative physical, mental…...
Do Polygenic Scores Predict Psychiatric Illness Better Than Variants?
1+ mon, 2+ week ago (422+ words) Both recurrent copy number variants (rCNVs) and polygenic scores (PGSs) show important diagnostic implications for psychiatric mental disorders, but remain largely exploratory, according to study findings published in JAMA Psychiatry. Certain rCNVs have near-complete penetrance for psychiatric disorders; however, their…...
Psychiatric Condition Rates Elevated in Pediatric Neurodevelopmental Disorders
1+ mon, 3+ week ago (266+ words) Researchers conducted an umbrella review and meta-analysis to determine the prevalence of co-occurring psychiatric conditions among children and adolescents with NDDs and compared these rates with those observed in neurotypical populations. Researchers included 33 systematic reviews. Child participants were between the…...
Shared White Matter Changes Link Chromosome 6p Deletion With ADHD Symptoms
2+ mon, 1+ week ago (208+ words) Researchers conducted a structured literature search to examine white matter changes in chromosome 6p deletion and compare them with white matter signatures established in pediatric patients with ADHD. Additionally, researchers aimed to emphasize the clinical relevance of early parental education and…...
Pediatric Neuropsychiatric Disorders Share Genetic Architecture With Ocular Defects
2+ mon, 1+ week ago (275+ words) A total of 2726 participants with ADHD and 16,299 control individuals were included for analysis from CAG at CHOP. The age range for both cohorts was between 3 and 21 years, with a mean age of 6 years. In the validation cohort, the genetic risk…...
Schizophrenia Shows Increased Risk for Cardiac Repolarization Heterogeneity
3+ mon, 2+ day ago (195+ words) After systematic screening, 5648 patients with schizophrenia and 23,636 control individuals were included for analysis. Most studies had a NOS score between 5 and 9, or moderate to high quality. The primary outcomes were frontal QRS-T angle, Tpeak-Tend (Tp-e) interval, and Tp-e/QT ratio,…...
ADHD With SUD Comorbidity Linked to Higher Risk for Treatment Discontinuation
3+ mon, 1+ week ago (554+ words) Individuals with vs without attention-deficit/hyperactivity disorder (ADHD) and comorbid substance use disorder (SUD) are likely to discontinue pharmacologic treatment and less likely to resume therapy, according to study results published in BMJ Mental Health. Researchers conducted a population-based, matched…...
Early ADHD Therapy Does Not Reduce Long-Term Substance Use Outcomes
3+ mon, 3+ day ago (275+ words) Children aged 7 and younger with attention-deficit/hyperactivity disorder (ADHD) who receive parent-child interaction therapy (PCIT) vs other psychosocial interventions plus medication do not have better long-term reduction in substance use. These study findings were published in the Journal of Child…...
Magnetic Seizure Therapy Noninferior to RUL-UB ECT for Major Depression
3+ mon, 5+ day ago (295+ words) Magnetic seizure therapy appeared to beneficial for the treatment of major depressive disorder with fewer memory-related risks. HealthDay News — For adults with major depressive disorder, magnetic seizure therapy (MST) is noninferior to right unilateral ultra-brief pulse-width (RUL-UB) electroconvulsive therapy (ECT)…...