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Key timepoint, neuron type, and cellular functions identified for schizophrenia risk gene
1+ hour, 9+ min ago (769+ words) Researchers at King's College London have identified the biological nature and timing of changes in human cortical neurons caused by altering activity of a schizophrenia-associated gene in developing human neurons. This discovery links a genetic risk factor to cellular changes…...
Profs & Pints Northern Virginia: Psychedelic-Assisted Therapy | ARLnow
10+ hour, 56+ min ago (58+ words) Profs and Pints Northern Virginia presents: "Psychedelic-Assisted Therapy," on findings, debates and trends in the use of psychedelic substances to treat trauma and other conditions, with Whitney Marris, instructor at the University of Buffalo's School of Social Work, certified psychedelic-assisted…...
Schizophrenia Risk Gene Linked to Hyper-Excitable Neurons
1+ hour, 13+ min ago (707+ words) Summary: A precision functional genomics study successfully mapped the biological timing and cellular consequences of a major schizophrenia-associated gene. The research investigates ZNF804 A, the very first risk gene identified from human genomic data, and pinpoints its peak activity during a…...
Serotonin reduces "belief stickiness," which could explain how it works on people with OCD
1+ hour, 18+ min ago (707+ words) A study co-authored by a Brown University computational cognitive neuroscientist showed how an SSRI improves cognitive flexibility, suggesting a new way of thinking about obsessive-compulsive disorder. PROVIDENCE, R. I. [Brown University] " In exploring how serotonin affects how people learn and adapt to…...
Scientists link schizophrenia risk gene to early cortical neuron changes
2+ hour, 59+ min ago (460+ words) Schizophrenia is estimated to be one of the most heritable psychiatric conditions, with a strong developmental aspect. Large scale human genomic studies have'identified'many genetic variants which are thought to increase the likelihood of schizophrenia.' This new research, published in Science…...
Most college students with psychosis lack recommended combination treatment
2+ hour, 52+ min ago (282+ words) Although the majority of students sought and received therapy or counseling in the past 12 months, less than 40 percent received the recommended combination of therapy/counseling and antipsychotic medication, suggesting potential barriers to accessing this medication. Published in the journal Social…...
IL-6 Drug Promising in Depression; U. S. More Anxious; AI Risks in Addiction Medicine
3+ hour, 4+ min ago (336+ words) A single infusion of the interleukin (IL)-6 inhibitor tocilizumabopens in a new tab or window (Actemra) showed greater improvements in depression severity, somatic symptoms, fatigue, and anxiety in patients with difficult-to-treat depression and low-grade inflammation compared with placebo in a proof-of-concept…...
Feature-specific threat coding in lateral septum guides defensive action
18+ hour, 35+ min ago (1694+ words) Nature (2026) Cite this article Sequencing data have been deposited in the Gene Expression Omnibus (GEO) under accession number GSE298976. Owing to the complexity of the data structure, additional data are available upon request from the corresponding authors. Risold, P. Y. & Swanson, L. W. Connections of…...
Immunotherapy could be used to treat depression, early trial suggests
1+ hour, 27+ min ago (398+ words) Immunotherapy could be used to treat depression among patients who have not responded to conventional antidepressants, according to the results of an early clinical trial. About one in three people with depression do not get better while taking the main…...
Greater risk of schizophrenia among people with HIV " especially those who inject drugs
9+ hour, 20+ min ago (776+ words) While the risk of being diagnosed with schizophrenia was higher among all people with HIV in a large Danish cohort, those who acquired HIV through injecting drug use were at a much higher risk. This research also highlights the complex…...