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Single dose of potent psychedelic drug could help treat depression, trial shows
3+ min ago (630+ words) Researchers find DMT " used in shamanic rituals " in tandem with psychotherapy has significant effect People with major depressive disorder can see a rapid and lasting improvement after a single dose of the psychedelic drug dimethyltryptamine (DMT) when it is combined…...
A short-acting psychedelic intervention for major depressive disorder: a phase IIa randomized placebo-controlled trial - Nature Medicine
3+ hour, 23+ min ago (1296+ words) Nature Medicine (2026)Cite this article Major depressive disorder (MDD) is a leading cause of disability worldwide, substantially affecting individuals" quality of life and creating a substantial public health burden1,2. All participants tolerated the dosing sessions well, except for one individual who expressed…...
Low-dose psilocybin reduces weight gain and hyperglycemia in mice fed obesogenic diet
3+ hour, 56+ min ago (366+ words) A study of mice fed a high-fat/high-fructose diet (designed to induce obesity) found that 12 weeks of treatment with low-dose psilocybin reduced weight gain, symptoms of fatty liver, hyperglycemia, and insulin resistance. It did not produce observable effects on the…...
Single Dose of DMT Rapidly Reduces Symptoms of Major Depression
5+ hour ago (694+ words) In an early clinical trial, a single dose of a short-acting psychedelic drug led to rapid improvement in people with major depressive disorder. The study included 34 patients with moderate-to-severe depression, all of whom had tried other treatments without success. Those…...
Psychedelic reduces depression symptoms after just one dose
5+ hour, 2+ min ago (456+ words) The psychedelic DMT has been linked to improved mental health outcomes before, but now, scientists have shown it reduces depression symptoms more than a placebo when given alongside therapeutic support Psychedelics may enable the brain to form new connections A…...
Psychedelic found in ayahuasca shows anti-depression promise
5+ hour, 3+ min ago (510+ words) Michael Peel in London A psychedelic compound found in the Amazonian hallucinogenic brew ayahuasca quickly curbed clinical depression sufferers" symptoms, according to research on how drugs used socially could treat mental health disorders. "When it comes to treating depression we…...
Just one dose of psychedelic drug reduced depression in a week: Study
5+ hour, 3+ min ago (532+ words) Feb 16, 2026 at 11:00 AM EST Feb 16, 2026 at 11:59 AM EST Americans Are Socializing Less, Is It Making Us Unhappy? Woman Experiences Abdominal Pain and Bloating, Horror at What Scan Reveals Family and Parenting Reporter A psychedelic drug known for its intense but…...
Polygenic score for C-reactive protein is linked to faster cortical thinning and psychopathology risk in adolescents - Nature Mental Health
6+ hour, 51+ min ago (1683+ words) Nature Mental Health (2026)Cite this article Participants were stratified by imputed genetic ancestry into European and non-European samples to account for population stratification, and results were integrated using meta-analysis to enhance generalizability across diverse populations (Fig. 1). Statistical significance was determined…...
Brief intense exercise more effective in treating panic disorder than standard care, study suggests
8+ hour, 39+ min ago (457+ words) A study suggests that brief, intense intermittent exercise might be more effective in treating panic disorder, compared to standard care which involves psychotherapy sessions. Cognitive behavioral therapy (CBT) is a form of psychotherapy that helps an individual develop strategies to…...
Depression May Warn of Parkinson's or Dementia, Years Before Diagnosis
9+ hour, 3+ min ago (698+ words) Researchers have found compelling evidence that depression points to the development of Parkinson's disease or Lewy body dementia later in life, with depressive symptoms often appearing several years before signs of a neurological condition. A team from Aarhus University in…...