15+ hour, 11+ min ago  (1652+ words) npj Mental Health Research volume5, Articlenumber:13 (2026) Cite this article Overall, considering the objective data produced by the ring, the subjective (e-VAS) data provided by the participants, and the various time periods, we created a set of 49 variables (see Supplementary Table 1). Classifier…...

2+ day, 6+ hour ago  (1726+ words) A Flowchart of the UG task; B spatial normalization of task-based peak activation from standard to native space in a representative participant; C the individualized target coordinates of each patient in standard MNI space; D cTBS treatment schedule and schematic…...

5+ day, 2+ hour ago  (1753+ words) CREB and CREB-CBP pharmacological inhibition: For restricting the interaction of CREB with its co-transcriptional activator CBP, a specific KIX-KID interaction inhibitor was used (CAS 92-78-4; Millipore/Sigma Aldrich) and was added at a concertation of 2.5M. To quantify the accuracy of CDR1as as…...

5+ day, 2+ hour ago  (1758+ words) Further analysis revealed significant difference between four profiles across six cognitive sub-dimensions except for the social cognition dimension. There are significant differences in the total and general psychopathology PANSS scores among the four profiles of patients with SCZ (Supplementary Table1). In…...

6+ day, 4+ hour ago  (1296+ words) Nature Medicine (2026)Cite this article Major depressive disorder (MDD) is a leading cause of disability worldwide, substantially affecting individuals" quality of life and creating a substantial public health burden1,2. All participants tolerated the dosing sessions well, except for one individual who expressed…...

6+ day, 7+ hour ago  (1683+ words) Nature Mental Health (2026)Cite this article Participants were stratified by imputed genetic ancestry into European and non-European samples to account for population stratification, and results were integrated using meta-analysis to enhance generalizability across diverse populations (Fig. 1). Statistical significance was determined…...

1+ week, 1+ day ago  (1719+ words) Several of the samples data have been uploaded to the NIMH Data Archive. Analytic codes are available upon request. A subset of participants (n=204; 22%) completed a version of the EEfRT that used points as rewards instead of monetary rewards (i.e., $1.00 was…...

1+ week, 2+ day ago  (1689+ words) Nature Mental Health (2026)Cite this article We next examined the longitudinal changes of the two stratified neural factors across ages 14, 19 and 23 (Fig. 1e). While both the externalizing and internalizing neural factors maintained consistently high FC strengths throughout ages 14, 19 and 23 (all t…...

1+ week, 2+ day ago  (1668+ words) Behavioral and lipid data were tested for normality and compared between CUMS and control groups using independent t-tests or Mann'Whitney U tests, with categorical variables assessed by chi-square. Multiple behavioral endpoints were corrected using FDR (adjusted P" Feature selection in…...

1+ week, 2+ day ago  (1693+ words) The HAM-D score at Week 4 was missing for one participant (Week 6 score was available). Reduction in HAM-D score at Week 4 was estimated by fitting an exponential decay function to the remaining HAM-D reduction scores for this participant (Week 03). The Unbiased…...