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Microbial Legacy: Mycobacterium vaccae ATCC 15483 T intergenerationally diversifies the microbiome and enhances stress resilience in male mice - Molecular Psychiatry

3+ day, 13+ hour ago  (1708+ words) Molecular Psychiatry (2026) Cite this article Maternal behavior was observed daily throughout the first week following birth (postnatal days 16, except on postnatal day 3) as described previously with slight modifications [36]. For details, see supplementary materials and methods (Section1. 2). All dams were tested for…...

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Nature
nature. com > articles > s41380-026-03628-x

White matter microstructure in relatives of people with schizophrenia or bipolar disorder: an ENIGMA meta-analysis - Molecular Psychiatry

4+ day, 13+ hour ago  (519+ words) Molecular Psychiatry (2026) Cite this article We analyzed data from a total of 2510 participants (age range: 672; see Table1) across 11 study sites from 7 countries worldwide (see Supplementary Fig. 1; note that 8 of the study sites also contributed to analyses of gray matter [17]). Finally, for…...

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nature. com > articles > s41386-026-02442-x

Resting-state functional connectivity of the default mode network as a predictor for escitalopram response in adolescents with depression | Neuropsychopharmacology

4+ day, 13+ hour ago  (1714+ words) All adolescents included in the study were medication-na've, and approximately 80% were experiencing their first depressive episode at the time of enrollment, whereas the remaining participants had a history of at least one prior depressive episode. The prevalence of comorbid diagnoses…...

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Nature
nature. com > articles > s41398-026-04103-5

Superior colliculus modulates the compulsion in a model of addiction with foot-shock - Translational Psychiatry

4+ day, 13+ hour ago  (124+ words) This study was supported by the National Key Research and Development Program of China (2023 YFC3304201). The graphical abstract created with Bio GDP. com. State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Department of Pharmacology, School of Basic…...

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Nature
nature. com > articles > s41380-026-03654-9

Rethinking schizophrenia: insights from genomics and implications for research - Molecular Psychiatry

4+ day, 13+ hour ago  (1732+ words) Molecular Psychiatry (2026) Cite this article Nevertheless, from the clinical and research perspectives, comparison of within and between diagnosis genetic correlations suggests that, while current diagnostic criteria may not define biologically distinct conditions, they do identify groups of cases whose members…...

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Nature
nature. com > articles > s41586-026-10520-9

Feature-specific threat coding in lateral septum guides defensive action

5+ day, 13+ hour ago  (1694+ words) Nature (2026) Cite this article Sequencing data have been deposited in the Gene Expression Omnibus (GEO) under accession number GSE298976. Owing to the complexity of the data structure, additional data are available upon request from the corresponding authors. Risold, P. Y. & Swanson, L. W. Connections of…...

Nature
nature. com > articles > s41380-026-03641-0

Cerebral cortical alterations in adolescent early-onset psychosis: a surface-based morphometry mega-analysis - Molecular Psychiatry

6+ day, 13+ hour ago  (1761+ words) Molecular Psychiatry (2026) Cite this article Cortical brain morphology in early-onset psychosis (EOP; age of onset Statistical analyses were conducted in R (v4. 2. 4) [57]. For each cortical metric and set of analyses, we controlled the False Discovery Rate (FDR) with the Benjamini-Hochberg procedure…...

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nature. com > articles > s44277-026-00062-3

Personalized machine learning guided intervention for optimizing lifestyle behaviors in depression: a pilot study | NPP'Digital Psychiatry and Neuroscience

6+ day, 12+ hour ago  (1728+ words) The sample size of 50 participants accounted for up to 20% attrition, so as to obtain at least 40 complete study samples that were powered to detect a statistically meaningful medium effect size (Cohen's d>0. 45) primary outcome difference in pre vs post comparisons…...

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nature. com > articles > s44220-026-00649-x

The Precision Mental Health Commission: transforming mental health through brain circuit science | Nature Mental Health

1+ week, 13+ hour ago  (291+ words) Nature Mental Health (2026) Cite this article This Comment announces the Precision Mental Health Commission and its initiative to redefine mental disorders through brain circuit function analysis, promoting stratified, circuit-informed care that enhances treatment accuracy and efficiency. The approach mirrors advances…...

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nature. com > articles > s41562-026-02475-8

Polygenic risk scores are not genetic predispositions | Nature Human Behaviour

1+ week, 13+ hour ago  (202+ words) Nature Human Behaviour (2026) Cite this article Kullo, I. J. Nat. Rev. Genet. 27, 246263 (2026). Moore, D. S. , Kampourakis, K. & Gericke, N. Hum. Dev. 69, 147157 (2025). Dar-Nimrod, I. & Heine, S. J. Psychol. Bull. 137, 800818 (2011). Furrer, R. , Carmi, S. , Lencz, T. & L'zaro-Mu'oz, G. Am. J. Bioeth. 23, 4244 (2023). Turkheimer, E. Psychol. Rev. 105, 782791 (1998). Kachuri, L. et al. Nat. Rev. Genet. 25, 825 (2024). Bates, G. P. et al. Nat. Rev. Dis....