3+ hour, 12+ min ago  (1677+ words) Twenty-six years ago, researchers at Yale University made a surprising discovery when a small group of patients with major depressive disorder (MDD) showed improved symptoms after a single dose of intravenous (IV) ketamine. Since then, other studies have added weight to the…...

6+ day, 23+ hour ago  (693+ words) Compared with usual care, genotype-guided prescribing of selective serotonin reuptake inhibitors (SSRI) in children and adults with depression didn't improve symptoms at 3 months but was associated with higher remission rates at 6 months, results of a large randomized trial revealed. While…...

1+ week, 2+ day ago  (893+ words) F. Perry Wilson, MD, MSCE Associate Professor, Department of Medicine and Public Health, Yale School of Medicine; Director, Clinical and Translational Research Accelerator, Yale School of Medicine, New Haven, Connecticut" Disclosure: F. Perry Wilson, MD, MSCE, has disclosed no relevant financial relationships....

1+ week, 3+ day ago  (570+ words) An expanding pipeline of novel psychiatric medications with persistently thin evidence and significant safety concerns for older adults is fostering caution in prescribing among geriatricians, according to experts who reviewed emerging antipsychotics and insomnia treatments at the American Geriatrics Society…...

2+ mon, 3+ week ago  (239+ words) In that context, the pathophysiology of PMS and PMDD and potential therapeutic approaches were analyzed at length by Anne-Laure Sutter'Dallay, MD, Ph D, perinatal psychiatrist at Charles Perrens University Hospital in Bordeaux, France. PMS and PMDD are characterized by symptoms…...

1+ mon, 3+ week ago  (1391+ words) Beneath this patient's otherwise coherent presentation was postpartum psychosis, a severe psychiatric emergency that can include delusions, paranoia, and mania. "Most patients could be hiding in plain sight," Birndorf said. But "if you can identify them, if people have access…...

1+ mon, 4+ week ago  (531+ words) There is insufficient or low-quality evidence to suggest cannabinoids are effective at treating most psychiatric conditions and substance use disorders (SUDs), results from one of the largest systematic reviews and meta-analyses to date showed. Additionally, there was a greater increase…...

1+ mon, 4+ week ago  (402+ words) Medscape Anxiety and Depression May Raise Risk for Aneurysm Rupture Edited by Vineeta Teotia Anxiety or depression after a diagnosis of unruptured intracranial aneurysms (UIAs) was associated with a 33% increased risk for rupture and a 28% higher risk for mortality compared…...

2+ mon, 2+ week ago  (1085+ words) Add to Email Alerts A new expert consensus statement from the American Society of Clinical Psychopharmacology offered clinical guidance on when and whether to discontinue psychiatric medications. The statement, developed by a 45-member international task force, reached consensus on 44 of…...

2+ mon, 2+ week ago  (677+ words) Cannabis use in adolescence was associated with a significantly greater likelihood of developing serious psychiatric disorders " particularly psychosis and bipolar disorder " in early adulthood compared to no cannabis use, a large longitudinal cohort study found. Researchers analyzing electronic health record…...