News
IL-6 Drug Promising in Depression; U. S. More Anxious; AI Risks in Addiction Medicine
3+ hour, 48+ min ago (336+ words) A single infusion of the interleukin (IL)-6 inhibitor tocilizumabopens in a new tab or window (Actemra) showed greater improvements in depression severity, somatic symptoms, fatigue, and anxiety in patients with difficult-to-treat depression and low-grade inflammation compared with placebo in a proof-of-concept…...
Brain Changes Tied to Single Psilocybin Dose; 50 Days to See Neurology; APOE4 and MS
2+ week, 1+ day ago (248+ words) A single 25-mg dose of psilocybin was associated with lasting anatomical brain changes, an imaging study of 28 healthy, psychedelic-naive participants showed. (Nature Communications) A high-sensitivity digital seed amplification assay detected markers of frontotemporal lobar dementia with TDP-43 in a test…...
Chat GPT Flops for Psychotic Prompts; ADHD Drug and Psychosis; Metabolic Psychiatry
1+ mon, 2+ week ago (321+ words) Three different versions of Chat GPT showed high ratesopens in a new tab or window of inappropriate or partially appropriate responses to psychotic prompts, with the free version performing the worst. (JAMA Psychiatry) Social media doesn't need to be so…...
High-Dose Psychedelic Beats Nicotine Patches for Smoking Cessation
2+ mon, 1+ week ago (588+ words) A single high-strength dose of psilocybin was more effective than nicotine patches for helping smokers quit, a pilot randomized trial showed. When added to cognitive behavioral therapy (CBT), 40. 5% of participants who received one dose of psilocybin (30 mg/70 kg) abstained from…...