4+ day, 2+ hour ago  (580+ words) Antidepression treatment based on a person's individual biomarkers could help determine which of the world's most popular medications to use, a clinical trial suggests. The SMART Trial to Predict Anhedonia Response to Antidepressant Treatment results suggest that behavioral, brain, and…...

1+ week, 4+ day ago  (407+ words) Many DNA variants linked with neuropsychiatric disorders (NPD) that do not code for proteins depend on neuronal activation, a study suggests. The findings, in Science, highlight the power of cell stimulation to reveal context-specific "hidden" genetic effects in conditions such…...

1+ mon, 1+ day ago  (545+ words) A comprehensive international genetics study found several new genetic risk factors for Alzheimer's disease and related dementias, providing one of the clearest pictures of the biological pathways that cause the devastating neurodegenerative disorder. Published in the journal Nature Genetics, the…...

1+ mon, 2+ week ago  (324+ words) Longstanding links between attention-related problems and changes in the brain's cortex during childhood and adolescence could simply be due to developmental differences between the sexes, a study suggests. The findings, in PNAS, showed that links between attention problems and slowed…...

2+ mon, 1+ day ago  (390+ words) Prescribing antidepressants according to a patient's genetic makeup could help manage depressive symptoms in the long-term, a clinical trial suggests. The findings, in JAMA Network Open, suggest pharmacogenetic guidance could have extended benefits, which may not be apparent early on....

2+ mon, 1+ day ago  (351+ words) Research led by New York University suggests a marker of epigenetic aging could be linked to depression. The team found that accelerated aging of a type of white blood cell called a monocyte was significantly associated with the psychological and…...