News
Long'Range Gene Networks Uncover 641 New Schizophrenia'Associated Genes
13+ hour, 1+ min ago (425+ words) A new gene'network modeling framework integrating cis and trans regulatory effects identifies 766 schizophrenia'associated genes641 previously missedacross six brain regions. The post Long'Range Gene Networks Uncover 641 New Schizophrenia'Associated Genes appeared first on GEN - Genetic Engineering and Biotechnology News....
Potential Cocaine Addiction Targets Identified Through Genetic Mapping in Rats
1+ week, 4+ day ago (203+ words) Current research in this field often focuses on the brain, but the UC San Diego team's findings suggest that how the body metabolizes cocaine may be just as critical in determining whether somebody develops an addiction. "The extended access model…...
Brain Histamine Map Links Genetic Factors to Mental Health and Psychiatric Disorders
1+ mon, 1+ week ago (737+ words) Genetic Engineering and Biotechnology News A study headed by researchers at King's College London and the University of Porto has mapped the histamine system in the brain. Histamine, a molecule more commonly associated with allergies, plays a separate but poorly…...
Psilocybin-Induced Brain Changes May Explain Therapeutic Effects
1+ mon, 2+ week ago (340+ words) Researchers at University of California, San Francisco and Imperial College London have shown that a single dose of psilocybin, the psychedelic compound found in magic mushrooms, causes likely anatomical brain changes that last for up to a month after the…...
Mapping the Neural Mechanism Behind Social Isolation Following Immune Challenge
6+ mon, 3+ week ago (299+ words) Our findings show that social isolation following immune challenge is self-imposed and driven by an active neural process, rather than a secondary consequence of physiological symptoms of sickness, such as lethargy," said study co-senior author Gloria Choi, Ph D, associate…...
Novel Schizophrenia Biomarker and Potential Therapeutic Strategy Identified
3+ mon, 3+ day ago (1151+ words) Researchers identified in humans a novel biomarker of schizophrenia, which studies in mice indicated could also serve as a new drug candidate that corrects overexcited brain circuits to treat cognitive symptoms of the disorder. The post Novel Schizophrenia Biomarker and…...
Multilevel Genomic Analysis Links Schizophrenia and Osteoporosis
5+ mon, 2+ week ago (351+ words) Credit: Tanya Joy / i Stock / Getty Images Plus Previous attempts to quantify this overlap yielded mixed results. Standard methods such as linkage disequilibrium score regression captured only average correlations across the genome, potentially missing regional hotspots of shared risk. The…...
AI Detects Schizophrenia and Bipolar Disorder Neural Signatures in Organoids
9+ mon, 17+ hour ago (194+ words) Neurological disorders, such as schizophrenia and bipolar disorder, remain challenging to diagnose due to the absence of objective biomarkers. Current assessments largely rely on subjective clinical evaluations." Kathuria's team engineered the organoids by converting blood and skin cells from schizophrenic,…...
Psychedelics and Non-Hallucinogenic Analogs Share Neuroplasticity Pathway
10+ mon, 2+ week ago (318+ words) A brain and psychedelic drugs [wildpixel / 1306005226 / i Stock / Getty Images Plus] The team found that TBG promotes neuroplasticity by activating the same psychedelic receptor as 5-Me O-DMT, but to a different extent. The researchers also provide the first direct evidence…...