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News
Ketamine increases neuroplasticity in female mice but not in males
2+ day, 1+ hour ago (559+ words) EurekAlert! Alessandro Venturino and Sandra Siegert, scientists at the Institute of Science and Technology Austria Credit: Siegert group, Institute of Science and Technology Austria (ISTA) Doctors use ketamine on patients as general anesthesia before surgery. They also prescribe it in…...
Immune signals may help explain, predict responses to therapies for difficult-to-treat depression
2+ day, 18+ hour ago (173+ words) image: These panels display a type of brain wave activity known as gamma power, which reflects the brain's ability to form and strengthen connections, in patients with high levels of IL-7 in treatment-resistant depression (red) and following ketamine treatment (blue). view…...
Plasma proteomic signatures of childhood adversity
1+ week, 5+ day ago (382+ words) EurekAlert! This study provides the most comprehensive disease-proteome atlas of childhood adversity to date, reveals plasma proteins as key mediators of associations between childhood adversity and disease, and presents a proteomic childhood adversity score that improves disease risk prediction beyond…...
Brain imaging now reveals muscarinic dysfunction in living patients with schizophrenia
2+ week, 2+ day ago (118+ words) Credit: Biological Psychiatry / Volpi et al. “The study’s findings were robust across multiple methods of PET quantification and remained significant after accounting for potential confounding factors, including gray matter differences and partial-volume effects” says co-first author Tommaso Volpi, MD, PhD,…...
C1 neurons identified as a driver of prolonged fear and anxiety
3+ week, 3+ day ago (278+ words) Credit: St. Jude Children's Research Hospital “C1 neurons appear to promote anxiety without directly affecting autonomic functions,” Schwarz said. “This suggests they may be a better target than broadly affecting signaling across the entire brain and body.” C1 neurons sound the alarm…...
First randomized controlled trial shows promise of a ketogenic diet in psychotic disorders
3+ week, 4+ day ago (523+ words) EurekAlert! Summary of results from UCSF study "Metabolic improvements with a ketogenic diet correlate with symptom improvement in psychosis: A randomized controlled trial" Published today in Schizophrenia Bulletin, a first-of-its-kind randomized controlled trial (RCT) from researchers at the University of…...
Just one exposure to cocaine alters mouse brain cells for two weeks
3+ week, 5+ day ago (570+ words) image: Ana Pombo view more Credit: FENS Forum / Ana Pombo Barcelona, Spain: Researchers studying the impact of cocaine in mice have found that just one exposure to the drug can create changes in brain cells that persist for at least…...
Pilot trial suggests anti-inflammatory drug could help difficult-to-treat depression
2+ mon, 2+ week ago (366+ words) Immunotherapy could be a promising new treatment option for patients with difficult-to-treat depression. This is a key finding from a University of Bristol-led pilot randomised controlled clinical trial, published in JAMA Psychiatry today [20 May]. Researchers investigated, for the first time,…...
Lower dopamine may drive teen risk-taking that fades with age
1+ mon, 3+ week ago (271+ words) image: Ashley Parr, Ph.D. view more PITTSBURGH, June 11, 2026 – Teenage risk-taking, such as experimentation with alcohol, cannabis, nicotine and other substances, may reflect a compensatory response to lower baseline dopamine, the brain chemical for reward activity, suggests a new University of…...
How does childhood trauma get embedded in the body? New study uncovers mechanisms linking fear learning, brain function and inflammation
1+ mon, 3+ week ago (182+ words) image: Brain regions of interest involved in fear learning, including the amygdala, hippocampus, ventromedial prefrontal cortex (vmPFC), and dorsal anterior cingulate cortex (dACC). view more Credit: Yuanyuan Chen, Rushan Liu, and Jianjun Zhu Childhood maltreatment is known to exert long-lasting…...