4+ hour, 30+ min ago   (23+ words) Cureus Download Cureus Media Kit Public user content licensed CC-BY 4.0...

1+ week, 3+ day ago   (478+ words) People with schizophrenia-spectrum disorders die 15-20 years prematurely, predominantly from cardiovascular disease, and antipsychotic-induced weight gain is a major, partly iatrogenic contributor to this excess mortality. Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are potent weight-lowering agents that are increasingly used as metabolic…...

3+ week, 17+ hour ago   (279+ words) The co-occurrence of dermatological and psychiatric conditions has long been recognized, owing in part to the shared ectodermal origin of the skin and the nervous system. Vitiligo, an autoimmune depigmenting disorder, and schizophrenia, a chronic psychotic illness increasingly associated with…...

3+ week, 1+ day ago   (545+ words) Background and objective Antipsychotic-associated metabolic abnormalities, including weight gain, dyslipidemia, hyperglycemia, obesity, and metabolic syndrome, vary among drugs. Receptor pharmacology offers mechanistic clues, while transcriptome-wide association studies identify genetically regulated expression signals linked to lipid traits. These evidence streams are…...

3+ week, 1+ day ago   (51+ words) Tocilizumab Therapy and Incident Depression in Rheumatoid Arthritis: A Retrospective Cohort Study of the All of Us Research Program cureus.com Please note that by doing so you agree to be added to our monthly email newsletter distribution list. Download…...

1+ mon, 6+ day ago   (212+ words) Fucosidosis is an exceptionally rare autosomal recessive lysosomal storage disorder caused by deficiency of α-L-fucosidase due to pathogenic variants in the FUCA1 gene. Neurologic involvement is prominent, and magnetic resonance imaging (MRI) frequently provides early diagnostic clues through characteristic white matter…...

1+ mon, 1+ week ago   (344+ words) A 16-year-old post-pubertal female presented with mixed anxiety-depressive symptoms, prominent obsessive rumination, relationship-centered guilt, reassurance-seeking, fantasy intrusions, and difficulty separating fantasy from reality during periods of distress. Baseline scores were in the moderate range for depression and severe range for…...

1+ mon, 1+ week ago   (217+ words) The intersection of pediatric psychiatry and infectious disease can present complex diagnostic challenges, particularly when symptoms of organic medical etiology mimic severe psychiatric disorders. This case study analyzes the clinical trajectory of an adolescent patient who developed delirious mania - a…...

1+ mon, 2+ week ago   (297+ words) Lithium remains a cornerstone in the treatment of bipolar I disorder because of its well-established efficacy in reducing mood episode recurrence and suicide risk. However, its narrow therapeutic index makes patients particularly susceptible to clinically significant toxicity, especially following medication…...

1+ mon, 2+ week ago   (321+ words) Background Psychiatric EDs manage high volumes of patients who often face barriers to medication access, limited understanding of discharge instructions, and difficulty securing timely outpatient follow-up. Structured early outreach has shown promise in improving these transitions. This quality improvement initiative…...