News
Acute Laryngeal Dystonia Following Haloperidol Administration: Early Recognition Prevents Intubation
13+ hour, 25+ min ago (210+ words) Acute laryngeal dystonia (ALD) is a rare but potentially fatal extrapyramidal adverse effect of high-dose antipsychotic medications like haloperidol. It presents with sudden contraction of laryngeal muscles that causes narrowing of the airway, which rapidly progresses to'respiratory failure if not…...
Depression as a Risk Factor for Dementia and Cognitive Decline in Type 2 Diabetes Mellitus: A Systematic Review of Longitudinal Studies
1+ week, 1+ day ago (298+ words) Depression is highly prevalent among individuals with type 2 diabetes mellitus (T2DM) and has been increasingly recognized as a potential contributor to adverse cognitive outcomes. While both depression and diabetes independently increase the risk of cognitive decline and dementia, their combined impact…...
The Crossroads of Neurodegeneration: Exploring the Overlap Between Alzheimer's Disease and Depression
1+ week, 2+ day ago (221+ words) Alzheimer's disease (AD) and depression are two prevalent and debilitating neuropsychiatric disorders that frequently occur together and share overlapping clinical and molecular features. Understanding shared features of AD and depression is critical for delaying disease progression and improving quality of…...
Remission of Psychotic Symptoms Following Seizures in a Patient With an Episodic Psychotic Disorder
1+ week, 3+ day ago (192+ words) The relationship between psychosis and seizure activity has long been of clinical interest and historically contributed to the development of convulsive therapies in psychiatry. We report the case of a 36-year-old woman with an episodic psychotic disorder who presented with…...
Knowledge, Attitudes, and Practices Toward Perinatal Depression Among Obstetric Healthcare Professionals at a Tertiary Care Center in Mumbai, India
1+ week, 4+ day ago (245+ words) Background Perinatal depression is a common mental health condition with substantial adverse consequences for maternal well-being and child development. In India, obstetric healthcare professionals are often the first and most consistent point of contact for women during the antenatal and…...
Precision Psychiatry and the Clinical Meaning of Waiting
2+ week, 3+ day ago (181+ words) Psychiatric practice is characterized by uncertainty in diagnosis, prognosis, and treatment response, making waiting a common and often prudent clinical strategy. Despite its central role in everyday care, the clinical meaning of waiting is rarely examined explicitly. This editorial argues…...
Transient Mood Elevation Without a Manic Switch: Goldenseal-Augmented Oral Glutamatergic Regimen in Bipolar Depression With Comorbid Obsessive-Compulsive Disorder (OCD)
2+ week, 4+ day ago (211+ words) Treating bipolar depression that comes with obsessive, looping thoughts can be tricky because standard antidepressants often help only a little and can sometimes push the mood too high. In this report, we followed a 32-year-old man whose low mood and…...
Management of Poor Treatment Adherence in Teenage-Onset Bipolar I Disorder Using Long-Acting Injectable Second-Generation Antipsychotics: A Case Report
2+ week, 5+ day ago (190+ words) Bipolar disorder is a chronic episodic illness in which poor treatment adherence is a major contributor to relapse, repeated hospitalization, and functional decline. We report the case of a 22-year-old self-employed man, diagnosed with bipolar I disorder at 16 years of…...
Heart Rate Variability and Cognitive Function as Potential Endophenotypes in Schizophrenia: A Cross-Sectional Observational Study Using First-Degree Relatives
3+ week, 5+ day ago (417+ words) Background Heart rate variability (HRV) represents beat-to-beat fluctuations in heart rate arising from the dynamic balance between sympathetic and parasympathetic nervous system activity. Altered HRV reflects autonomic dysregulation and has been reported across several psychiatric disorders, including schizophrenia, where it…...
Cardiovagal Tone in Generalised Anxiety Disorder: A Case Control Study
1+ mon, 1+ day ago (324+ words) Introduction Generalised anxiety disorder (GAD) is a prevalent psychiatric condition increasingly associated with autonomic nervous system dysfunction. Specifically, impaired cardiovagal tone, a marker of reduced parasympathetic modulation of cardiac function, has been linked to emotional dysregulation, behavioural rigidity, and elevated…...