3+ hour, 59+ min ago   (173+ words) "[T]he routine use of cannabinoids for the treatment of mental disorders and SUDs is rarely justified." Investigators found limited evidence supporting cannabinoid use across many mental and substance use disorders, with evidence of symptom reduction reported in cannabis use…...

1+ week, 2+ day ago   (228+ words) Researchers developed the MDM System, which assigns one point for each metabolite exceeding the highest value observed in the typically developing reference group. Children with ASD had an average MDM total score of 3.3, while all typically developing children scored zero....

3+ week, 1+ day ago   (317+ words) Conexiant Patients with posttraumatic stress disorder may exhibit coordinated molecular changes involving redox metabolism, neuronal signaling, immune activation, and accelerated biological aging Researchers identified distinct plasma protein and metabolite signatures associated with chronic posttraumatic stress disorder In a study, they…...

1+ mon, 5+ day ago   (179+ words) Conexiant This Neuroscience Grand Rounds session, led by Yasaman Movahedi and Deanna Aghbashian, explores psychosis in adolescence through both clinical and neurocognitive lenses, emphasizing early recognition and multidisciplinary management Early-onset psychosis is associated with significant cognitive impairments, including deficits in…...

1+ mon, 3+ week ago   (169+ words) Lower cognition is associated with later depression in controls, while higher cognition is associated with relapse in remitted depression Participants with remitted depression had a higher risk of future depression compared with matched controls, while baseline cognitive performance was associated…...

2+ mon, 3+ day ago   (197+ words) Psychotic-like experiences were assessed using the Prodromal Questionnaire–Brief Child Version (PQ-BC), a self-report screening instrument measuring subclinical symptoms such as unusual perceptions, suspiciousness, and odd beliefs rather than diagnosed psychotic disorders. Scores were distress weighted on a scale ranging…...

2+ mon, 1+ week ago   (458+ words) Conexiant...

2+ mon, 2+ week ago   (312+ words) The cohort had a mean follow-up of 8.2 years. Women with premenstrual disorders had a mean age of 35 years at diagnosis. In the matched cohort analysis, 37% of women with premenstrual disorders developed a subsequent psychiatric disorder during follow-up compared with 21% of…...

2+ mon, 2+ week ago   (634+ words) The findings, however, should be considered preliminary and hypothesis-generating, according to both the study researchers and an accompanying invited commentary, because the trial included only 40 patients, had no prespecified power calculation, and faced substantial challenges with blinding and treatment attribution....

3+ mon, 2+ week ago   (183+ words) Impulsivity-linked brain patterns identified a subtype with a markedly higher 2-year risk for developing internet gaming disorder. A neuroimaging-defined subtype had a substantially higher 2-year risk for developing internet gaming disorder than a lower-risk subtype, with conversion rates of 24% vs…...