News
Autobahn on the fast track with bipolar thyroid agonist
1+ day, 2+ hour ago (20+ words) Bio World News Autobahn on the fast track with bipolar thyroid agonist...
Plasticity, properly parsed, provides psychiatric platform
1+ mon, 1+ week ago (71+ words) If Benjamin Braddock, of The Graduate fame, were a young neuroscientist in the 21st century instead of a liberal arts graduate in 1967, the advice he received from his parents" neighbor might not have been "One word: plastics!" but "One word: plasticity!...
With transdiagnostic approach, smaller target groups aren't inevitably smaller markets
7+ mon, 1+ day ago (76+ words) Despite the formidable challenges for developing precision psychiatry, the approach is notching its first successes in the preclinical and even some clinical settings. Many individual studies as well as large projects like the Psychiatric Ratings using Intermediate Markers (PRISM) studies…...
Precision psychiatry beyond, or before, biomarkers
2+ mon, 3+ week ago (70+ words) There is broad agreement that psychiatric diagnoses in their current form are not reflective of any underlying biology, and that this is one of the things hampering psychiatric drug development. "We are still fully reliant on descriptive diagnoses that yield…...
TRPC1 mediates pathological plasticity in fragile X syndrome mice
10+ mon, 2+ week ago (144+ words) Fragile X syndrome (FXS), the most common inherited cause of intellectual disability and autism, is caused by silencing of the Fmr1 gene, leading to a lack of the FMRP protein, which regulates protein synthesis in neurons. One key pathway affected by…...
Study: GLP-1 RAs associated with less risk of mental illness getting worse
2+ mon, 2+ week ago (71+ words) In a sea of uncertainty, a large-scale, long-term Swedish study is the first to show that people using GLP-1 receptor agonists are less likely to have worsening mental illness. The study involved a national cohort of 95, 490 people diagnosed with depression…...
Australia publishes first clinical practice guideline for psychedelics
2+ mon, 2+ week ago (17+ words) Bio World Med Tech Australia publishes first clinical practice guideline for psychedelics...
Compass nears NDA; psilocybin scores again in resistant depression
3+ mon, 2+ week ago (19+ words) bioworld. com Compass nears NDA; psilocybin scores again in resistant depression...
Serotonin receptor modulators for the treatment of OUD
4+ mon, 1+ week ago (17+ words) Bio World Med Tech Serotonin receptor modulators for the treatment of OUD...