17+ hour, 6+ min ago   (494+ words) A new study suggests that'people born more recently are being diagnosed with psychotic disorders (e.g., schizophrenia) more often and at younger ages compared with people born'earlier.' We don't yet know what's driving these changes, and it's likely there isn't a single…...

1+ week, 3+ day ago   (253+ words) Schizophrenia is a severe mental health condition that affects millions worldwide. While previous studies have established that schizophrenia is highly heritable and polygenic, most genetic research has focused on individuals of European ancestry. This bias has limited the applicability of…...

1+ week, 3+ day ago   (686+ words) Schizophrenia is a highly heterogeneous psychiatric disorder affecting ~1% of the global population, typically emerging in adolescence or early adulthood and characterized by hallucinations, delusions, disorganized thinking, and cognitive impairments; while its etiology remains elusive, genetic factors are widely recognized as…...

1+ week, 6+ day ago   (182+ words) Schizophrenia affects people across all regions and backgrounds, yet most genetic studies to date have focused on individuals of European ancestry. This imbalance has limited scientific understanding of the disorder and reduced the accuracy of genetic tools for millions of…...

2+ week, 1+ day ago   (252+ words) Psychiatrists and neuroscientists are taking a major step toward objective mental health diagnosis by launching a central reference database for the classification and communication of mental health biomarker research. Central reference database launched to categorize and coordinate mental health biomarker…...

3+ week, 13+ hour ago   (305+ words) Schizophrenia is a neuropsychiatric disorder that affects around 1% of the population and is best known for its hallucinatory and delusional symptoms. However, it is also marked by profound apathy, a reduced ability to experience pleasure, and progressive social withdrawal. These…...

3+ week, 6+ day ago   (198+ words) Exercise may reduce symptoms of depression to a similar extent as'psychological therapy, according to an updated Cochrane review.'When compared with antidepressant medication, exercise also showed a similar effect, but the evidence was of low certainty.' "Our findings suggest that…...

4+ week, 1+ hour ago   (322+ words) Could ketamine's effects on inhibitory neurons explain some of its remarkable properties as a rapid-acting antidepressant? And what might this reveal about the fundamental organization of neural circuits? These questions connected her pharmacological observations to deeper mysteries about brain development....

4+ week, 3+ hour ago   (459+ words) An elevated neutrophil-to-lymphocyte ratio (NLR) is significantly associated with increased risk of depressive disorder (DD) and may also correlate with suicide risk among individuals with DD, according to a systematic review and meta-analysis published in the November issue of Harvard Review…...

4+ week, 11+ hour ago   (523+ words) The human genome held clues that traditional clinical observation could never detect. Both schizophrenia and osteoporosis are highly heritable conditions, each influenced by thousands of genetic variants scattered across chromosomes. If even a fraction of those variants overlapped, it would…...