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Frontiers | Personalized resilience: how individual variability in brain–immune responses to stress influences the development of anxiety disorders
17+ hour, 22+ min ago (358+ words) Stress exposure has increased significantly, contributing to higher rates of anxiety, depression, and post-traumatic stress disorder. However, individual responses to stress vary greatly, underscoring the concept of stress resilience. The acute stress response activates the amygdala, hippocampus, and prefrontal cortex,…...
Efficacy and safety of desvenlafaxine in treating patients with major depressive disorder: a network meta-analysis
3+ day, 17+ hour ago (1304+ words) Front. Neurosci., 06 February 2026 Conclusion: DVS at doses " 50 mg/day significantly improves depressive symptoms compared with placebo. Among the evaluated doses, 200 mg/day consistently showed numerically greater improvements while maintaining acceptable tolerability; however, the certainty of dose differences remains limited, and…...
Integrating autonomic and affective pathways in borderline personality disorder: the triangle therapy hypothesis
1+ week, 17+ hour ago (1596+ words) HYPOTHESIS AND THEORY article Front. Psychol., 02 February 2026 1. Silence " neuroception of abandonment " dorsal vagal collapse 2. Chaotic sound " neuroception of intrusion " sympathetic arousal 3. Prolonged isolation " neuroception of irrevocable aloneness " oscillation between sympathetic protest and dorsal shutdown TTB conceptualizes borderline dysregulation as emerging…...
Frontiers | Sexual hallucinations and delusions in borderline personality disorder
1+ week, 4+ day ago (541+ words) Introduction: Sexual hallucinations have lifetime prevalence rates of 0.4% in the general population and up to 44% in schizophrenia spectrum disorders. For borderline personality disorder (BPD) these rates are unknown. We therefore studied prevalence rates of sexual hallucinations and delusions in this…...
Olink proteomics identifies FGF-19 as a treatment-responsive inflammatory biomarker associated with acupuncture intervention in young females with mild depression
1+ week, 4+ day ago (305+ words) Mild depression in women is a distinct disorder with unclear immune mechanisms. This study aims to identify peripheral inflammatory biomarkers and to explore acupuncture's immunomodulatory effects via Olink proteomics. Thirty female participants (1845 years) were assigned to healthy controls (HC), mild…...
Bridging Electrophysiological Markers from Preclinical to Clinical Neuropsychiatric Research
1+ week, 4+ day ago (237+ words) Electrophysiology has emerged as a central pillar in the intersection of neuroscience and the treatment of neuropsychiatric disorders. Recent advancements in... You will be redirected to our submission process. About this Research Topic Manuscript Summary Submission Deadline 3 March 2026 | Manuscript Submission…...
The triglyceride-glucose index in relation to psychotic symptoms in adolescents with major depressive disorder
1+ week, 5+ day ago (1728+ words) Front. Psychiatry, 28 January 2026 This article is part of the Research TopicAdolescent Emotional Disorders and Suicide Self-Harm Crisis InterventionView all 38 articles Conclusions: Analysis of the dose-response relationship revealed a J-shaped curve linking the TyG index to psychotic symptoms among adolescents with…...
Frontiers | A COSMIN-Based Systematic Review of the Measurement Properties of Cross-Cultural Versions of the Orthorexia Nervosa Inventory (ONI)
2+ week, 4+ hour ago (461+ words) BackgroundOrthorexia nervosa (ON) has received increasing attention, and the Orthorexia Nervosa Inventory (ONI) is among the most widely used instruments to assess ON. As ON research expands globally, multiple countries have translated and culturally adapted the ONI. However, the methodological…...
Stress-induced epigenome changes as a risk factor in the onset of mental disorders (Review)
2+ week, 8+ hour ago (344+ words) The global mental health study has revealed a steady increase in the prevalence of mental disorders worldwide. This trend reflects not only the improvements in diagnostics but also the global population ageing and the intensification of negative environmental impacts that…...
Differences in height, weight, and BMI in patients with mood disorders, schizophrenia, and other mental disorders vs. normal controls
3+ week, 17+ hour ago (1763+ words) Front. Psychiatry, 19 January 2026 This article is part of the Research TopicBipolar Disorder: Where are we now? Treatment Response, Neural Correlates and PersonalityView all 4 articles Introduction: The literature suggests differences in the body between the general population and patients with mental…...