News
Alcohol impacts gene expression differently across brain regions
2+ week, 4+ day ago (364+ words) Erica Periandri and Gabor Egervari, from Washington University in St. Louis, led a study to explore how alcohol exposure in male mice influences gene expression and mechanisms that regulate gene function-or epigenetics. Alcohol impacts gene expression differently across brain regions…...
Key risk factors identified for long-term relapse in alcohol use disorder
2+ mon, 2+ week ago (448+ words) John F. Kelly, Ph D, of the Recovery Research Institute and Department of Psychiatry at Mass General Brigham, is the lead author of a paper published in Frontiers in Public Health, "Long-term relapse: markers, mechanisms, and implications for disease management in…...
Lithium shifts circadian rhythms early in bipolar disorder and may offer clues to treatment response
1+ year, 3+ day ago (190+ words) Can lithium's effect on daily activity patterns reveal who will benefit from treatment? A six-week trial finds circadian shifts emerge early, before mood improves, hinting at a biological clue to lithium response in bipolar disorder. Study: Effect of lithium on…...
Parents' genes shape children's mental health beyond inherited DNA
2+ day, 16+ hour ago (442+ words) The effects are small, the researchers emphasise, but the findings provide new knowledge about how psychological vulnerability can be transmitted across generations. We have long known that parents matter greatly for children's mental health. What is new in our study…...
Emerging neuromodulation techniques for treatment-resistant obsessive-compulsive disorder
5+ mon, 2+ week ago (518+ words) The review traces this transformation from early experimental attempts to a robust field guided by imaging, electrophysiology, and computational modeling. The authors emphasize that these tools do not replace existing therapies but complement them, creating a continuum from noninvasive stimulation…...
New $4. 4 million grant funds first study of prefrontal cortical stimulation in severe bipolar disorder
5+ mon, 2+ week ago (245+ words) A University of Minnesota Medical School research team, led by'Ziad Nahas, MD, has been awarded a $4. 4 million grant for a first-in-the-world study of prefrontal cortical stimulation in severe bipolar disorder. The funding, from Breakthrough Discoveries for thriving with Bipolar Disorder…...
BD" expands global effort to examine the key mechanisms of bipolar disorder
5+ mon, 3+ week ago (722+ words) Today, BD, or Breakthrough Discoveries for thriving with Bipolar Disorder, announced its third round of Discovery Research grants, totaling nearly $18 million " expanding a comprehensive global effort to examine the key mechanisms of bipolar disorder. BD expands global effort to examine…...
Largest bipolar disorder dataset launched to advance personalized care
2+ week, 4+ day ago (409+ words) BD: Breakthrough Discoveries for thriving with Bipolar Disorder today announced the first public release of data from the BD Integrated Network Longitudinal Cohort Study (LCS). This marks the launch of the largest integrated dataset in the history of psychiatry, designed…...
Understanding the role of paraventricular thalamic nucleus in bipolar disorder pathophysiology
7+ mon, 1+ week ago (553+ words) Bipolar disorder (BD) is a chronic mental health condition characterized by recurrent episodes of depression and mania. It poses a substantial burden on global health, with an increasing incidence. Understanding the role of paraventricular thalamic nucleus in bipolar disorder pathophysiology…...
Mindfulness-based therapy found to decrease opioid cravings and improve emotional health
11+ mon, 2+ week ago (808+ words) Researchers from the University of California San Diego have found that Mindfulness-Oriented Recovery Enhancement (MORE) can help rewire the brain's response to natural healthy pleasure, leading to improved mood, greater attention to positive experiences and reduced opioid cravings. Mindfulness-based therapy…...